Based at the University of Michigan's Ann Arbor campus, the S. M. Wu Manufacturing Research Center (WuMRC) is a College of Engineering Center with participating faculty and researchers from the Departments of Mechanical Engineering (ME) and Industrial and Operations Engineering (IOE). The WuMRC also has ties with over 60 industrial partners, including General Motors, Chrysler, Ford, Boeing, and many of their suppliers. In addition, many of the research projects have been supported by various government agencies including National Science Foundation, National Institute of Standards and Technology (ATP Programs), Department of Defense, and Department of Energy.

The Center for Intelligent Maintenance Systems (IMS) is an NSF I/UCRC which was co-established in 2001 by U of M and the University of Wisconsin-Milwaukee. Currently, the multi-campus Center is composed of research teams from U of M, the University of Cincinnati, and Missouri University of Science and Technology. The Center focuses on developing and disseminating technologies which foster "near-zero breakdown" through "predict and prevent" maintenance techniques. By serving the interests of private industry, government, and academia, the IMS Center has developed into a renowned resource for research, education, information transfer, and technology evaluation & deployment.

The Shien-Ming Wu Foundation is a not-for-profit 501 (C) (3) organization established to promote the advancement of manufacturing sciences and engineering.